%0 Journal Article
%T A Case Report of Early-Onset Alzheimer's Disease Using 18F-FDG PET and 18F-FBB PET.
%A Yoo J
%A Cheon M
%A Kang MJ
%J Diagnostics (Basel)
%V 13
%N 10
%D 2023 May 9
%M 37238154
%F 3.992
%R 10.3390/diagnostics13101671
%X We describe a 40-year-old female patient who presented with sleep disturbance, intermittent headache, and gradual subjective cognitive decline. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed mild FDG hypometabolism in bilateral parietal and temporal lobes. However, 18F-florbetaben (FBB) amyloid PET revealed diffuse amyloid retention in the lateral temporal cortex, frontal cortex, posterior cingulate cortex/precuneus, parietal cortex, and cerebellum. This finding supports the clinical significance of amyloid imaging in diagnostic work-up of early-onset Alzheimer's disease (EOAD).