%0 Case Reports %T Case Report: Lepromatous Leprosy Masquerading as Acute Suppurative Lymphadenitis. %A Meena M %A Joshi R %A Yadav V %A Singh P %A K S %A Pandey G %J Am J Trop Med Hyg %V 109 %N 1 %D 2023 07 5 %M 37188342 %F 3.707 %R 10.4269/ajtmh.22-0513 %X Leprosy is a chronic cutaneous infection. It is usually characterized by thickened nerves and maculo-anesthetic patches. Leprosy often has an unusual presentation, which is a diagnostic challenge. In this case report, we present a case of an elderly male who presented with fever and chronic pus-draining axillary, cervical, and inguinal lymph nodes. He also had a weak left foot for the previous 5 months. During his hospital stay, he developed additional papular lesions over his extremities. We performed fine needle aspiration from the lymph nodes and skin biopsy, which were suggestive of lepromatous leprosy. We initiated him on antileprosy medication. On follow-up, he was responsive to therapy. Although skin and nerve involvement in leprosy is common, this case had an atypical presentation of discharging lymph nodes.