%0 Case Reports
%T Pseudoseptic reaction to an intra-articular platelet-rich plasma injection into the knee: a case report.
%A Sung K
%A Zheng K
%A Williams C
%A Cunningham D
%A Sussman WI
%J Regen Med
%V 18
%N 6
%D 2023 06 15
%M 37183432
%F 3.21
%R 10.2217/rme-2022-0216
%X A variety of intra-articular injections are used for the management of osteoarthritis. A rare complication of intra-articular injections is acute pseudoseptic arthritis, which mimics true septic arthritis. To the authors knowledge, pseudosepsis has not been reported as a complication after platelet-rich plasma (PRP) injections. We present a case report of pseudoseptic arthritis resulting in acute postinjection pain and a joint effusion after an intra-articular PRP injection into the knee. Clinically, pseudosepsis can occur after PRP treatment with significantly elevated white blood cell counts in the synovial fluid, and should be a consideration in cases of post-PRP injection flares.