%0 Journal Article %T Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature. %A Paggi R %A Mariotti F %A Mencarini J %A Bresci S %A Campolmi I %A Bartalesi F %A Borchi B %A Nassi L %A Sordi B %A Vannucchi AM %A Bartoloni A %J Mediterr J Hematol Infect Dis %V 15 %N 1 %D 2023 %M 37180207 %F 3.122 %R 10.4084/MJHID.2023.028 %X The use of specific inhibitory drugs of intracellular signalling pathways (such as Bruton-Kinase inhibitors) for the treatment of Waldenström's macroglobulinaemia (WM) is a recognised risk factor for Aspergillus spp. infections. The overlapping clinical manifestations of the two diseases may require the involvement of different medical specialities. We describe the clinical course of a patient with pulmonary and encephalic aspergillosis, with concomitant orbital infiltration, which represented a difficult diagnosis: the case required a multidisciplinary approach to define the ocular lesions and an in-depth study of the literature.