%0 Case Reports %T Intraoperative awake language mapping correlates to preoperative connectomics imaging: An instructive case. %A Shah HA %A Ablyazova F %A Alrez A %A Wernicke AG %A Vojnic M %A Silverstein JW %A Yaffe B %A D'Amico RS %J Clin Neurol Neurosurg %V 229 %N 0 %D 2023 06 29 %M 37149972 %F 1.885 %R 10.1016/j.clineuro.2023.107751 %X Connectomics enables the study of structural-functional relationships in the brain, and machine learning technologies have enabled connectome maps to be developed for individual brain tumor patients. We report our experience using connectomics to plan and guide an awake craniotomy for a tumor impinging on the language area. Preoperative connectomics imaging demonstrated proximity of the tumor to parcellations of the language area. Intraoperative awake language mapping was performed, revealing speech arrest and paraphasic errors at areas of the tumor boundary correlating to functional regions that explained these findings. This instructive case highlights the potential benefits of implementing connectomics into neurosurgical planning.