%0 Journal Article
%T A large-cohort study of 2971 cases of epulis: focusing on risk factors associated with recurrence.
%A Zhao N
%A Yesibulati Y
%A Xiayizhati P
%A He YN
%A Xia RH
%A Yan XZ
%J BMC Oral Health
%V 23
%N 1
%D 2023 04 20
%M 37081478
%F 3.747
%R 10.1186/s12903-023-02935-x
%X To analyze the clinicopathological features of different histological subtypes of epulis, and evaluate the risk factors associated with recurrence.<BR>A retrospective study including 2971 patients was performed. The patients' sex, age, location, size, histological subtypes, recurrence information, oral hygiene habits, periodontitis symptoms and smoking history were retrieved from the patient medical records and follow-up information.<BR>Among the 2971 cases, focal fibrous hyperplasia (FFH) was the most common lesion (60.92%), followed by peripheral ossifying fibroma (POF) (29.32%), pyogenic granuloma (PG) (8.08%) and peripheral giant cell granuloma (PGCG) (1.68%). The peak incidence of epulis was in the third and fourth decade of life, with a mean age of 45.55 years. Female predominance was found in all types of lesions with a female to male ratio of 1.71:1. PG had the highest recurrence rate (17.18%), followed by POF (12.98%), FFH (9.55%) and PGCG (8.82%). Histological subtypes were significantly correlated with the recurrence of epulis (P = 0.013). Regular supportive periodontal therapy (P = 0.050) had a negative correlation with recurrence, whereas symptoms of periodontitis (P < 0.001) had a positive correlation with the recurrence of epulis.<BR>Controlling the periodontal inflammation and regular supportive periodontal therapy might help reduce the recurrence of epulis.