%0 Journal Article
%T Four sesquiterpenes isolated from Taraxacum mongolicum.
%A Liu JB
%A Xie J
%A Wang HQ
%A Lai ST
%A Shao HJ
%A Chen RY
%A Kang J
%J J Asian Nat Prod Res
%V 25
%N 11
%D 2023 Nov 18
%M 37071690
%F 1.61
%R 10.1080/10286020.2023.2197225
%X One new sesquiterpene, (6S,7R,11S)-13-carboxy-1(10)-en-dihydroartemisinic acid (1), together with three known sesquiterpenes, ainsliaea acid B (2), mongolicumin B (3), and 11β,13-dihydroxydeacetylmatricarin (4) were isolated from Taraxacum mongolicum Hand.-Mazz. The structures were established on the basis of UV, IR, HR-ESI-MS, 1D and 2D NMR spectroscopy, ECD spectroscopy, and X-ray diffraction analysis. Compound 1 was found to have potential anti-inflammatory activity and could reduce LPS-induced NO levels in murine macrophage, with inhibitory rate of 37%.