%0 Journal Article
%T A narrative review on asthma and pest sensitization (cockroach, mouse and rat allergens): a social issue besides the medical problem.
%A Liccardi G
%A Martini M
%A Bilò MB
%A Milanese M
%A Calzetta L
%A Laitano R
%A Rogliani P
%J J Asthma
%V 60
%N 10
%D 10 2023 23
%M 37042228
暂无%R 10.1080/02770903.2023.2200844
%X Among animals defined as "pests", cockroaches and rodents (mouse and rat) represent the most common cause of airway allergic sensitization and bronchial asthma worldwide. Their frequency of sensitization has been widely assessed in US and other countries but poorly in Western Europe. This narrative review aims to provide a synthesis of data resulting in MEDLINE concerning allergic sensitization/asthma to pests as well as their related environmental/social risk factors, specifically in the European area.<BR>We performed a literature research in MEDLINE for clinical trials, randomized controlled trials, systematic reviews and meta-analyses.<BR>We selected studies to the following key words: allergic sensitization, allergic rhinitis, bronchial asthma, cockroach, hypersensitivity, integrated pest management, material hardship, medication compliance, mouse, pest, poverty, rat, rodents.<BR>Current evidence indicates that residence in poor and urban areas, exposure to outdoor/indoor pollutants and tobacco smoke, poverty, material hardship, poor-quality housing, differences in health care quality, medication compliance, health care access contribute to increased pest-related allergic sensitization and asthma morbidity.<BR>Further research should be done on many aspects of pest allergy such as a better characterization of allergens and epidemiological aspects. Relevant social actions should be carried out against poverty, healthcare disparities, psycho-social stress, poor compliance to therapy, with economic contributions to improve private and public living environments. Allergic sensitization to pests and pest-allergic respiratory diseases like asthma are "paradoxical" conditions, as they typically affect the poorest communities but can only be corrected by high-cost (diagnostic and preventive) interventions. We hope that progress can be made in this direction in the future.