%0 Journal Article
%T High-throughput screening of mutations affecting SARS-CoV-2 spike functions.
%A Xia S
%A Liu Z
%A Jiang S
%J Trends Immunol
%V 44
%N 5
%D 05 2023 29
%M 37031063
%F 19.709
%R 10.1016/j.it.2023.03.010
%X The spike (S) protein of SARS-CoV-2, which is undergoing rapid evolution, plays crucial roles in viral immune escape, infectivity, and transmissibility. To gain clinical insight, Dadonaite et al. developed a novel deep mutational scanning (DMS) platform for mapping the effects of S protein mutations on immune evasion and viral infectivity.