%0 Review
%T Preoperative n-BCA embolization in the resection of submandibular lymphatic malformations refractory to sclerotherapy treatment: A pilot case series.
%A Shum A
%A Beydoun AS
%A Khalifee E
%A Carlberg V
%A Plunk M
%A Chun R
%J Int J Pediatr Otorhinolaryngol
%V 168
%N 0
%D May 2023 15
%M 37003014
%F 1.626
%R 10.1016/j.ijporl.2023.111510
%X <B>OBJECTIVE: </B>Lymphatic malformations in the submandibular neck pose unique challenges to treatment that elevate their risk of recurrence. This case series provides a review of five patients, previously treated with sclerotherapy or with a history of multiple infections, who were treated in a novel fashion: single-stage resection using preoperative n-butyl cyanoacrylate (n-BCA) glue embolization.<BR><B>METHODS: </B>We performed a retrospective medical record review of five patients who underwent single-stage n-BCA embolization by Interventional Radiology followed by surgical resection by Otolaryngology, including a review of their symptoms, previous treatments, and post-treatment surveillance, with follow-up ranging from 4 to 24 months after the treatment of interest.<BR><B>RESULTS: </B>All study subjects had unremarkable perioperative courses, and four patients did not demonstrate any evidence of disease recurrence or persistence during the follow-up period. One patient was found to have a small area of persistent disease on post-treatment imaging, but has remained symptom free.<BR><B>CONCLUSIONS: </B>Treatment of submandibular lymphatic malformations with n-BCA embolization followed by surgical resection can be performed in a single stage. This case series demonstrates that this approach can yield durable relief of symptoms, even in patients whose lesions were refractory to previous treatments.