%0 Journal Article %T Endoreplication controls cell size via mechanochemical signaling. %A Bhosale R %A Vissenberg K %J Trends Plant Sci %V 28 %N 6 %D 2023 06 %M 36997439 %F 22.012 %R 10.1016/j.tplants.2023.03.016 %X During hypocotyl development, an asymmetric auxin gradient causes differential cell elongation, leading to tissue bending and apical hook formation. Recently, Ma et al. identified a molecular pathway that links auxin with endoreplication and cell size through cell wall integrity sensing, cell wall remodeling, and regulation of cell wall stiffness.