%0 Case Reports
%T HTLV-1-associated demyelinating neuropathy: A case report and review of the literature.
%A Tamaki K
%A Mishima T
%A Tateishi Y
%A Mera H
%A Ogura H
%A Tsugawa J
%A Fujioka S
%A Takamatsu Y
%A Tsuboi Y
%J eNeurologicalSci
%V 31
%N 0
%D Jun 2023
%M 36891478
暂无%R 10.1016/j.ensci.2023.100453
%X A 78-year-old man developed paresthesias in the extremities. He was referred to our hospital because of positive anti-human T-cell leukemia virus type 1 (HTLV-1) antibodies in the serum and the presence of abnormal lymphocytes. He was diagnosed as chronic-type adult T-cell leukemia/lymphoma. Neurological examination revealed sensory impairment in the distal parts of the extremities with loss of deep tendon reflexes. Nerve conduction study showed motor and sensory demyelinating polyneuropathy, indicating a diagnosis of HTLV-1-associated demyelinating neuropathy. Corticosteroid therapy followed by intravenous immunoglobulin therapy improved his symptoms. Since demyelinating neuropathy associated with HTLV-1 infection is not well recognized, we here report its characteristics and clinical course through our case report and literature review.