%0 Journal Article
%T Derivatives of sesquiterpenes, 2-furaldehyde, phenols, and alkaloids isolated from Taraxacum mongolicum.
%A Wang H
%A Xie J
%A Dong C
%A Lai S
%A Liu J
%A Shao H
%A Chen R
%A Kang J
%J Fitoterapia
%V 166
%N 0
%D Apr 2023
%M 36848964
%F 3.204
%R 10.1016/j.fitote.2023.105463
%X Four new compounds (1-4), together with 23 known compounds (5-27), were isolated from the whole plant of Taraxacum mongolicum. Among them, one racemic mixture (4) was separated with a chiral HPLC column. Their structures were identified by spectroscopic evidence and mass spectrometry. The absolute configurations of compounds 1, 3, and 4 were determined via comparison of their calculated and experimental electronic circular dichroism (ECD) spectra. Compound 3 showed an inhibitory effect against aldose reductase with a 59.1% inhibition. Two known compounds (13 and 27) showed α-glucosidase inhibition of 51.5% and 56.0%, respectively.