%0 Journal Article
%T The Early-Enhancing Hepatic Vein: Differentiating Focal Nodular Hyperplasia and Hepatic Adenoma With Pathologic Validation in MRI.
%A Kania LM
%A Dave J
%A Guglielmo FF
%A Naringrekar HV
%A Alturki A
%A Civan JM
%A Bundschuh MA
%A Mitchell DG
%J J Magn Reson Imaging
%V 58
%N 4
%D 10 2023 6
%M 36744579
%F 5.119
%R 10.1002/jmri.28629
%X Focal nodular hyperplasia (FNH) and hepatic adenoma (HA) are two common benign liver lesions with different management options. In particular, resection is considered for large HA lesions to avoid possible bleeding complications or rarely malignant degeneration.
To determine whether early enhancement of a draining hepatic vein (EDHV) and absence of perilesional enhancement (PLE) on arterial phase MR images are useful for distinguishing FNH from HA.
Retrospective.
A total of 34 patients: 16 with FNH and 18 with HA lesions.
A1.5āT, axial T1 fat-suppressed arterial postcontrast.
Four abdominal radiologists blinded to pathologic diagnosis assessed for the presence or absence of EDHV in association with the lesion, definitively characterized by pathology. This was considered present if contrast could be identified in a hepatic vein contiguous with the lesion in question. Secondarily, PLE was evaluated.
Fleiss's multirater kappa statistic, Chi-squared statistic, Phi-coefficient. Significance level Pā<ā0.05.
Considering all observations obtained from the four readers, an EDHV was identified with FNH 48.5% of the time. EDHV was seen with HA in 8.8% of cases. PLE was seen with significantly greater frequency in HA. The presence of an EDHV was associated with the absence of PLE.
In a lesion that may be either an FNH or HA, confident identification on arterial phase images of an EDHV should lead the reader to favor FNH, while the presence PLE should dissuade the reader from FNH.
4.
Stage 2.