%0 Case Reports %T Nagashima-type palmoplantar keratoderma: Case series and two novel variants. %A Braun M %A Choate KA %A Mathes EF %J Pediatr Dermatol %V 40 %N 5 %D Sep-Oct 2023 31 %M 36721328 %F 1.997 %R 10.1111/pde.15265 %X Nagashima-type palmoplantar keratoderma (PPK) is an autosomal recessive PPK. We report four patients, highlight two new genetic variants, and emphasize the possibility of misdiagnosing the condition. Concomitant atopic dermatitis, specifically, may make correct diagnosis challenging. Clinicians should consider the diagnosis of Nagashima-type PPK in patients presenting with mild PPK with transgrediens and understand the importance of individualized multimodal treatment regimens.