%0 Journal Article
%T Identification of the First Sulfobetaine Hydrogel-Binding Peptides via Phage Display Assay.
%A Ihlenburg RBJ
%A Petracek D
%A Schrank P
%A Davari MD
%A Taubert A
%A Rothenstein D
%J Macromol Rapid Commun
%V 44
%N 16
%D Aug 2023 26
%M 36703485
%F 5.006
%R 10.1002/marc.202200896
%X Using the M13 phage display, a series of 7- and 12-mer peptides which interact with new sulfobetaine hydrogels are identified. Two peptides each from the 7- and 12-mer peptide libraries bind to the new sulfobetaine hydrogels with high affinity compared to the wild-type phage lacking a dedicated hydrogel binding peptide. This is the first report of peptides binding to zwitterionic sulfobetaine hydrogels and the study therefore opens up the pathway toward new phage or peptide/hydrogel hybrids with high application potential.