%0 Case Reports
%T Acanthamoeba meningoencephalitis causing secondary hemophagocytic lymphohistiocytosis in an immunocompetent patient: A first case report.
%A Chowdhury M
%A Prakash PR
%A Singh A
%A Jorwal P
%A Das S
%A Soneja M
%J J R Coll Physicians Edinb
%V 53
%N 1
%D 03 2023 20
%M 36680356
暂无%R 10.1177/14782715221149709
%X Acanthamoeba is a rare cause of granulomatous amoebic encephalitis (GAE) associated with high mortality. There have been few case reports of Acanthamoeba meningoencephalitis worldwide. Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory condition caused by abnormally active macrophages and cytotoxic T lymphocytes; its secondary form is due to infections or malignancies. However, HLH is rather an unknown complication of GAE. We describe an unusual and previously unreported case of Acanthamoeba meningoencephalitis in a young immunocompetent female culminating in secondary HLH.