%0 Journal Article
%T Barrett's Esophagus: An Updated Review.
%A Stawinski PM
%A Dziadkowiec KN
%A Kuo LA
%A Echavarria J
%A Saligram S
%J Diagnostics (Basel)
%V 13
%N 2
%D Jan 2023 16
%M 36673131
%F 3.992
%R 10.3390/diagnostics13020321
%X Barrett’s esophagus (BE) is a change in the distal esophageal mucosal lining, whereby metaplastic columnar epithelium replaces squamous epithelium of the esophagus. This change represents a pre-malignant mucosal transformation which has a known association with the development of esophageal adenocarcinoma. Gastroesophageal reflux disease is a risk factor for BE, other risk factors include patients who are Caucasian, age > 50 years, central obesity, tobacco use, history of peptic stricture and erosive gastritis. Screening for BE remains selective based on risk factors, a screening program in the general population is not routinely recommended. Diagnosis of BE is established with a combination of endoscopic recognition, targeted biopsies, and histologic confirmation of columnar metaplasia. We aim to provide a comprehensive review of the epidemiology, pathogenesis, screening and advanced techniques of detecting and eradicating Barrett’s esophagus.