%0 Journal Article
%T Emerging Biomarkers in Alcohol-associated Hepatitis.
%A Im GY
%J J Clin Exp Hepatol
%V 13
%N 1
%D Jan-Feb 2023
%M 36647419
暂无%R 10.1016/j.jceh.2022.07.246
%X Alcohol-associated hepatitis (AH) is a clinical syndrome of jaundice, abdominal pain, and anorexia due to prolonged heavy alcohol intake. AH is associated with changes in gene expression, cytokines, immune response, and the gut microbiome. There are limited biomarkers to diagnose and prognosticate in AH, but several non-invasive biomarkers are emerging. In this review, clinical risk-stratifying algorithms, promising AH biomarkers like cytokeratin-18 fragments, genetic polymorphisms, and microRNAs will be reviewed.