%0 Journal Article %T Lung Cancer Screening Initiative in Slovakia: Guidelines of screening implementation. %A Juskanic D %A Sandor F %A Denkova L %A Juhos P %A Janik M %A Hontzas J %A Mistinova JP %A Senitko M %A Ondrusova M %J Bratisl Lek Listy %V 124 %N 2 %D 2023 %M 36598297 %F 1.564 %R 10.4149/BLL_2023_016 %X Lung cancer (LC) represents a major healthcare issue worldwide. It is the leading cause of cancer-related mortality in Slovakia and European Union. Data from multiple randomized controlled trials have shown significant evidence of a mortality benefit in LC using screening with low-dose computed tomography of the chest (LDCT). Therefore, European healthcare authorities, relevant expert societies, and professional organizations recommend implementing national LC screening (LCS) programs in their member countries. This article outlines the basic methodology, guidelines, and practical aspects of LCS implementation strategies in Slovakia. We describe fundamental principles to identify asymptomatic high-risk patients reduce false positive and false negative results, decrease benign resection rates, and avoid unnecessary invasive procedures. The efficacious utilization of public resources to secure the highest possible quality standards of LDCT plays a crucial role in successfully implementing a nationwide LCS program (Tab. 1, Fig. 4, Ref. 31). Text in PDF www.elis.sk Keywords: lung cancer, screening, early detection, smoking cessation.