%0 Case Reports
%T Frequent self-monitoring of intraocular pressure can determine effectiveness of medications in eyes with normal tension glaucoma: A case report.
%A Mizohata H
%A Ikesugi K
%A Kondo M
%J Medicine (Baltimore)
%V 101
%N 52
%D Dec 2022 30
%M 36595993
%F 1.817
%R 10.1097/MD.0000000000032478
%X <B>BACKGROUND: </B>It is difficult to follow changes in the intraocular pressure (IOP) in glaucomatous eyes comprehensively because of the limited number of outpatient examinations. We report our findings in a case of normal tension glaucoma (NTG) in which frequent self-measurements of the IOP were used to evaluate the IOP-lowering effect of different medications.<BR><B>METHODS: </B>A 50-year-old man with NTG had a nasal step visual field defect in his right eye and was being treated with 0.005% latanoprost (LAT) ophthalmic solution (XALATAN®).<BR><B>METHODS: </B>The patient was diagnosed with NTG.<BR><B>METHODS: </B>The patient had a mean IOP in the right eye of 10.9 ± 1.5 mm Hg (68 measurements in 1 month, Period A) during treatment with 0.005% LAT ophthalmic solution. During the second month (Period B), the mean IOP in the same eye was 9.8 ± 1.7 mm Hg (59 measurements) with treatment with a LAT and carteolol fixed combination (LCFC). And during the third month (Period C), the mean IOP was 7.4 ± 1.1 mm Hg (57 measurements) on the same right eye after the addition of brimonidine and brinzolamide fixed combination ophthalmic solution to the LCFC ophthalmic solution.<BR><B>RESULTS: </B>Comparisons of the IOPs between Periods A and B and between B and C showed that the reductions in the IOP were significant.<BR><B>CONCLUSIONS: </B>We conclude that frequent self-measurements of the IOP can determine that small changes of the IOPs are significant.