%0 Case Reports %T Modified facelift in severe plexiform neurofibromatosis associated with venous vascular malformation: Case report. %A Mayer HF %A Palacios Huatuco RM %A Petersen ML %A Garcia Rodriguez B %A Peralta OA %J Ann Chir Plast Esthet %V 68 %N 2 %D Apr 2023 %M 36543616 %F 0.75 %R 10.1016/j.anplas.2022.11.004 %X Neurofibromatosis is an autosomal dominant disorder characterized by tumors of the nervous system and skin. Plexiform neurofibromas are common complications of neurofibromatosis type 1 and can cause large facial deformities. Vascular anomalies are in turn a rare manifestation of neurofibromatosis. We present the case of a 48-year-old female patient with right hemifacial neurofibromatosis associated with venous vascular malformation, previously treated surgically and then with sclerosing agents, determining severe residual facial deformity. Her surgical approach using a modified facelift technique associated with partial tumor debulking and lipofilling seems to be a valid technical alternative for these highly complex cases that require a customized approach after exhaustive preoperative evaluation.