%0 Journal Article %T In Vitro Model Systems to Study Human T Cell Development. %A Lambrechts N %A Liang KL %A Velghe I %A Strubbe S %A Dolens AC %A Taghon T %J Methods Mol Biol %V 2580 %N 0 %D 2023 %M 36374468 暂无%R 10.1007/978-1-0716-2740-2_21 %X Not only is human T cell development characterized by unique changes in surface marker expression, but it also requires specific growth factors and conditions to mimic and study T cell development in vitro. In this chapter, we provide an overview of the specific aspects that need attention when performing T cell differentiation cultures with human hematopoietic and T cell progenitors.