%0 Journal Article
%T Signatures of Positive Selection in the Genome of Apis mellifera carnica: A Subspecies of European Honeybees.
%A Huang Q
%A Zhu YQ
%A Fouks B
%A He XJ
%A Niu QS
%A Zheng HJ
%A Zeng ZJ
%J Life (Basel)
%V 12
%N 10
%D Oct 2022 19
%M 36295077
%F 3.251
%R 10.3390/life12101642
%X The technology of long reads substantially improved the contingency of the genome assembly, particularly resolving contiguity of the repetitive regions. By integrating the interactive fragment using Hi-C, and the HiFi technique, a solid genome of the honeybee Apis mellifera carnica was assembled at the chromosomal level. A distinctive pattern of genes involved in social evolution was found by comparing it with social and solitary bees. A positive selection was identified in genes involved with cold tolerance, which likely underlies the adaptation of this European honeybee subspecies in the north hemisphere. The availability of this new high-quality genome will foster further studies and advances on genome variation during subspeciation, honeybee breeding and comparative genomics.