%0 Case Reports %T Unusual generalized tetanus evolving from odontogenic infection: A case report and review of recent literature. %A Akbar M %A Ruslin M %A Yusuf ASH %A Boffano P %A Tomihara K %A Forouzanfar T %J Heliyon %V 8 %N 9 %D Sep 2022 %M 36200020 %F 3.776 %R 10.1016/j.heliyon.2022.e10810 %X Tetanus is an acute and vaccine-preventable disease caused by anaerobic bacteria, Clostridium tetani. This bacterium can enter the human body via a deep wound, burn injury or medical procedure; however, certain cases also originate from odontogenic infection. In the present study, a tetanus infection associated with dental origin in a 44-year-old man is reported. The case was complicated by lockjaw and difficulty swallowing that worsened over a few days, followed by a generalized spasm. Furthermore, a literature review was performed, in which six reported cases of tetanus, presumed to be of dental or oral origin, were identified between 2011and 2021. General practitioners, especially dentists, should be aware of tetanus associated with odontogenic origin even without a history of an external penetrating wound or other medical procedures:.