%0 Case Reports
%T Investigating anti-D in an individual with the weak D type 2 genotype.
%A Phou S
%A Nguyen N
%A Revilla J
%A Rodberg K
%A Gibb DR
%A Pepkowitz SH
%A Klapper EB
%A Phou S
%A Nguyen N
%A Revilla J
%A Rodberg K
%A Gibb DR
%A Pepkowitz SH
%A Klapper EB
%A Phou S
%A Nguyen N
%A Revilla J
%A Rodberg K
%A Gibb DR
%A Pepkowitz SH
%A Klapper EB
%A Phou S
%A Nguyen N
%A Revilla J
%A Rodberg K
%A Gibb DR
%A Pepkowitz SH
%A Klapper EB
%J Immunohematology
%V 38
%N 3
%D Sep 2022 1
%M 36190200
暂无%R 10.21307/immunohematology-2022-046
%X Anti-D in individuals with a weak D phenotype is an unexpected finding that may require additional investigation to determine whether the anti-D is an autoantibody or alloantibody. Further investigation may also include assessment of the patient's RHD genotype and exclusion of anti-G. We present a case of an 84-year-old man with the weak D type 2 genotype who developed an unexpected anti-D along with anti-C. Individuals with the weak D type 2 genotype are thought not to be at risk for developing alloanti-D, although the distinction between alloanti-D and autoanti-D may be difficult to ascertain. Furthermore, investigations may affect transfusion recommendations. This patient was restricted to crossmatch-compatible, D-C- red blood cells even though the clinical significance of the anti-D was uncertain. This report is one of a few reported cases of an individual with the weak D type 2 genotype with demonstrable anti-D but without evidence for alloanti-D.