%0 Journal Article
%T Selective local postoperative radiotherapy for T3-T4 N0 laryngeal cancer.
%A Dağdelen M
%A Şahin M
%A Çatal TK
%A Yıldırım HC
%A Karaçam SÇ
%A Çepni K
%A Uzel ÖE
%J Strahlenther Onkol
%V 0
%N 0
%D Sep 2022 8
%M 36074137
%F 4.033
%R 10.1007/s00066-022-01999-y
%X <B>OBJECTIVE: </B>We aimed to investigate the appropriate postoperative radiotherapy dose and selective volume in T3-4 N0 laryngeal cancer patients treated with either total or partial laryngectomy.<BR><B>METHODS: </B>Patients who received radiotherapy for locally advanced (T3-T4) and pathologic node-negative (N0) squamous cell laryngeal cancer were retrospectively evaluated. Radiotherapy was applied to median 60 Gy (range 54-60 Gy) as selective local radiotherapy (±stoma). The local treatment areas included postoperative bed + laryngeal area for patients with a partial laryngectomy, and the postoperative bed only for patients with total laryngectomy.<BR><B>RESULTS: </B>The median follow-up time was 59 months and 52 patients were included. The 2‑year, 5‑year, and 8‑year locoregional recurrence controls (LRC) were 95.6%. The 2‑year and 5‑year OS rates were 93.8% and 78.9%, respectively. The 5‑year OS for age < 60 years was 95.8%, for above 60 years 56.5%.<BR><B>CONCLUSIONS: </B>Our data suggest that local selective irradiation to the postoperative bed + stoma is enough in patients with T3-4 N0 laryngeal cancer without applying elective nodal irradiation.