%0 Case Reports %T Spontaneous resolution of an intraosseous mandibular lesion: a case report and review of the literature. %A Kontaxis KL %A Chalich R %A Dakak I %A Kauzman A %J Gen Dent %V 70 %N 5 %D Sep-Oct 2022 %M 35993932 暂无%X The objective of this case report and review of the literature is to address spontaneously regressing radiolucent lesions affecting the mandible. In 2010, a 16-year-old girl presented with an impacted mandibular third molar associated with a radiolucent lesion. At that time, the treating clinician considered the lesion to be at high risk of causing life-threatening bleeding. Therefore, it was suggested that she not have her tooth extracted. The patient was lost to follow-up for 8 years. Recent radiographs obtained by an oral and maxillofacial surgeon revealed that the lesion had resolved spontaneously. This article also reviews and summarizes cases in the literature in which radiolucent mandibular lesions regressed without treatment or with minimal intervention such as aspiration or incisional biopsy. The current case report and previously reported findings of spontaneous regression underscore the importance of establishing an accurate differential diagnosis and highlight the benefits of a multidisciplinary approach involving general dentists, oral and maxillofacial radiologists, pathologists, and surgical colleagues for management of mandibular radiolucencies.