%0 Case Reports
%T Two smoking-related lesions in the same pulmonary lobe of squamous cell carcinoma and pulmonary Langerhans cell histiocytosis: A case report.
%A Gencer A
%A Ozcibik G
%A Karakas FG
%A Sarbay I
%A Batur S
%A Borekci S
%A Turna A
%A Gencer A
%A Ozcibik G
%A Karakas FG
%A Sarbay I
%A Batur S
%A Borekci S
%A Turna A
%J World J Clin Cases
%V 10
%N 19
%D Jul 2022 6
%M 35979280
%F 1.534
%R 10.12998/wjcc.v10.i19.6722
%X <B>BACKGROUND: </B>Pulmonary Langerhans cell histiocytosis (PLCH) is a rare cystic lung disease usually affecting young adults. It is predicted that PLCH is a lung tumor precursor associated with dysfunction of the myeloid dendritic cells in the lung.<BR><B>METHODS: </B>A 70-year-old male patient presented with chronic cough and sputum. He had symptoms for 5 years and described shortness of breath on exertion for the previous 3 years. He had a 60 packs/year smoking history. Computerized tomography of the thorax revealed an 11-mm nodule in the right lung lower lobe superior segment and a 7-mm nodule in the right lung lower lobe poster basal segment. Those two nodules were resected by means of right thoracoscopic surgery. Pathological evaluation revealed a squamous cell carcinoma and PLCH.<BR><B>CONCLUSIONS: </B>Coexistent squamous cell carcinoma and PLCH suggest possible association between PLCH and lung cancer.