%0 English Abstract
%T [Expert consensus on surgical treatment of tongue squamous cell carcinoma].
%A  
%A  
%J Zhonghua Kou Qiang Yi Xue Za Zhi
%V 57
%N 8
%D Aug 2022 9
%M 35970779
暂无%R 10.3760/cma.j.cn112144-20220530-00289
%X The annual incidence of oral cancer in the world is more than 300 000, and the five-year survival rate is 50%~60%. Every year, 145 400 people died due to tongue cancer, of which tongue cancer accounts for nearly 40%. Although tongue cancer has tumor heterogeneity and individual differences in prognosis, surgery is still the first choice for the treatment of tongue cancer. The effect of tongue cancer surgery can directly determine the survival time of patients. The defect caused by tongue cancer surgery seriously affects the patients' physical functions such as appearance, language, chewing and swallowing. The surgical treatment of tongue cancer with functional reconstruction can improve the quality of life of patients. In the past few decades, genomics has enhanced understanding of tongue cancer. The preclinical tumor model preserves the tumor heterogeneity, which has a great application prospect in the discovery of tumor biomarkers and the clinical translation of drugs. Many advances have been made in the diagnosis and treatment of tongue cancer, but there are still many controversies in clinical practice. Therefore, this expert consensus summarizes the progress and controversial hot spots of surgical diagnosis and treatment of tongue cancer, mainly including preoperative diagnosis and evaluation, surgical treatment points and postoperative functional rehabilitation.<BR>口腔癌在世界范围内的年发病人数超过300 000例，5年生存率为50%~60%，其中舌癌占比近40%。肿瘤存在肿瘤异质性，个体预后存在差异，但手术仍是治疗舌癌的第一选择。舌癌手术效果可直接决定患者的生存时间，其造成的损伤严重影响患者的外观、语言、咀嚼、吞咽等生理功能，舌癌的外科治疗必须兼顾功能重建，以提高患者的生存质量。在过去几十年里，人们对舌癌基因组学的认识不断深入，认识到临床研究前模型可以保存有肿瘤异质性，其在发现肿瘤标志物和药物临床转化中有巨大应用前景，舌癌的诊断和治疗取得了许多进展，但临床上对其诊疗仍存在诸多争论。因此，本专家共识总结了舌癌外科诊疗的进展和有争议的热点，主要涵盖了术前诊断评估、外科处理要点和术后功能康复等内容。.