%0 Case Reports
%T Sebaceous nevus of Jadassohn: review and clinical-surgical approach.
%A Neto MPDS
%A Assis BR
%A Andrade GR
%J An Bras Dermatol
%V 97
%N 5
%D Sep-Oct 2022
%M 35863943
%F 2.113
%R 10.1016/j.abd.2021.11.001
%X <B>BACKGROUND: </B>Nevus sebaceous of Jadassohn is defined as a rare congenital malformation characterized as a non-hereditary hamartoma of the adnexal structures of the skin. Its etiology is not yet well understood, but it is believed to be related to post-zygotic mutations in the HRAS, NRAS and KRAS genes.<BR><B>OBJECTIVE: </B>To describe the clinical manifestation of nevus sebaceous, as well as the main management techniques addressed in the medical literature. Moreover, the present study discusses a case report of a congenital linear nevus in the left retroauricular region found in a male patient, without extracutaneous manifestations.<BR><B>METHODS: </B>A narrative review of the literature was carried out.<BR><B>CONCLUSIONS: </B>Nevus sebaceous occurs as lesions with a linear or oval appearance, with a smooth or verrucous texture, generally alopecic and with very variable color. Moreover, nevus sebaceous is one of the components of the so-called linear nevus syndrome or Schimmelpenning-Feuerstein-Mims syndrome, which is associated with multisystemic complications. The treatment of the lesions is still controversial; however, most experts indicate surgical excision as the most frequently adopted treatment method, in addition to multidisciplinary follow-up when the diagnosis of Schimmelpenning-Feuerstein-Mims syndrome is established.<BR><B>CONCLUSIONS: </B>The linear nevus syndrome constitutes a rare manifestation; however, its diagnosis should be considered in children born with nevus sebaceous. There is no consensus yet on the best therapy, but surgical removal has shown to be a viable option.