%0 Journal Article
%T Epithelioid hemangioendothelioma in children: The European Pediatric Soft Tissue Sarcoma Study Group experience.
%A Orbach D
%A Van Noesel MM
%A Brennan B
%A Corradini N
%A Alaggio R
%A Ben Arush M
%A Schoot RA
%A Berlanga P
%A Zanetti I
%A Hjalgrim LL
%A Di Corti F
%A Ramirez G
%A Casanova M
%A Ferrari A
%J Pediatr Blood Cancer
%V 69
%N 10
%D Oct 2022
%M 35841307
%F 3.838
%R 10.1002/pbc.29882
%X The European pediatric Soft tissue sarcoma Study Group analyzed all children with epithelioid hemangioendothelioma prospectively registered in the NRSTS-05 (EUDRACT 2005-001139-31) and in MTS-2008 (NCT00379457) studies: 10 patients with localized and one with metastatic disease. Median age was 14.3 years (range, 9.0-18.8). Local therapy was initial primary surgery in seven cases, and five patients received systemic therapy. No patients received radiotherapy. After a median follow-up of 50 months (range, 6-176) for living patients, nine patients remain alive off therapy and two died. Five-year progression free and overall survivals are, respectively, 77.1% (95% confidence interval [CI]: 34.5-93.9) and 74.1% (95% CI: 28.1-93.0).