%0 Case Reports
%T Yellow nail syndrome accompanied by minimal-change nephrotic syndrome: A case report.
%A Zhang YN
%A Wang MH
%A Yu WC
%A Cheng W
%A Cong JP
%A Huang XP
%A Wang FF
%J World J Clin Cases
%V 10
%N 15
%D May 2022 26
%M 35801034
%F 1.534
%R 10.12998/wjcc.v10.i15.4949
%X <B>BACKGROUND: </B>In most cases of yellow nail syndrome (YNS), the classic triad of yellow nails, lymphedema and respiratory manifestations rarely manifest simultaneously. Therefore, diagnosis is delayed or frequently missed.<BR><B>METHODS: </B>We report a 62-year-old YNS patient presenting with bilateral pleural, pericardial and peritoneal effusions who, 2 mo later, developed minimal-change nephrotic syndrome. After treatment with vitamin E, clarithromycin and prednisone for 3 mo, effusions in the chest, pericardium and abdominal cavity decreased while urine protein levels returned to within normal ranges.<BR><B>CONCLUSIONS: </B>Clinicians should consider the possibility of YNS for patients presenting with multiple serous effusions and nephrotic syndromes.