%0 Journal Article
%T Phantom study of an in-house amplitude-gating respiratory method with silicon photomultiplier technology positron emission tomography/computed tomography.
%A Bailly P
%A Bouzerar R
%A Galan R
%A Meyer ME
%A Bailly P
%A Bouzerar R
%A Galan R
%A Meyer ME
%J Comput Methods Programs Biomed
%V 221
%N 0
%D Jun 2022
%M 35660941
%F 7.027
%R 10.1016/j.cmpb.2022.106907
%X <B>OBJECTIVE: </B>The objective of this phantom study was to determine whether breathing-synchronized, silicon photomultiplier (SiPM)-based PET/CT has a suitable acquisition time for routine clinical use.<BR><B>METHODS: </B>Acquisitions were performed in list mode on a 4-ring SiPM-based PET/CT system. The experimental setup consisted of an external respiratory tracking device placed on a commercial dynamic thorax phantom containing a sphere filled with [F-18]-fluorodeoxyglucose. Three-dimensional sinusoidal motion was imposed on the sphere. Data were processed using frequency binning and amplitude binning (the "DMI" and "OFFLINE" methods, respectively). PET sinograms were reconstructed with a Bayesian penalized likelihood algorithm.<BR><B>RESULTS: </B>Respiratory gating from a 150‑sec acquisition was successful. The DMI and OFFLINE methods gave similar activity profiles but both were slightly shifted in space; the latter profile was closest to the reference acquisition.<BR><B>CONCLUSIONS: </B>With SiPM PET/CT systems, the amplitude-based processing of breathing-synchronized data is likely to be feasible in routine clinical practice.