%0 Case Reports
%T Thyroid Storm in a Patient With Alemtuzumab-Induced Graves' Disease: A Case Report.
%A AlShehri S
%A Alajmi S
%A Ekhzaimy A
%A Aldawas S
%A Alalwan M
%J Cureus
%V 14
%N 4
%D Apr 2022
%M 35651398
暂无%R 10.7759/cureus.24570
%X Thyroid storm (TS) is a rare and life-threatening medical emergency, most commonly caused by Graves' disease (GD). GD can be induced by immune reconstitution therapy (IRT) such as alemtuzumab (ALZ), a humanized monoclonal antibody against CD52, which is shown to be effective in the treatment of relapsing-remitting multiple sclerosis (RRMS). Here, we present a rare case of TS developing in a 39-year-old female with ALZ-induced GD, managed with antithyroid medication followed by thyroidectomy. There is some evidence that ALZ-induced GD may behave less aggressively than conventional GD. However, physicians should be aware that severe thyrotoxicosis and thyroid storm can happen, which requires prompt recognition and aggressive therapy.