%0 Journal Article
%T Cerebellar syndrome associated with legionellosis: A case report and literature review.
%A Diallo K
%A Rivière M
%A Gutierrez B
%A Andry F
%A Bertolotti A
%A Zemali N
%A Saint-Pastou Terrier C
%A Manaquin R
%A Koumar Y
%A Poubeau P
%A Diallo K
%A Rivière M
%A Gutierrez B
%A Andry F
%A Bertolotti A
%A Zemali N
%A Saint-Pastou Terrier C
%A Manaquin R
%A Koumar Y
%A Poubeau P
%J Rev Med Interne
%V 43
%N 7
%D Jul 2022
%M 35643782
%F 0.885
%R 10.1016/j.revmed.2022.04.023
%X <B>BACKGROUND: </B>Legionnaire's disease is a community-acquired pneumonia caused by the Gram-negative bacterium Legionella pneumophila. This disease is often associated with neurological symptoms, the clinical presentation of which can be very varied.<BR><B>METHODS: </B>We report a 47-year-old female patient who developed Legionnaires' disease with cerebellar symptoms (ataxia, dysarthria and hypermetria). Laboratory tests revealed a biological inflammatory syndrome. The cerebrospinal fluid was sterile. Urinary antigen test and serology were positive for L. pneumophila. An interstitial syndrome of the right upper lobe was detected on chest computed tomography (CT) scan. Brain imaging (magnetic resonance imaging and CT angiography) showed no abnormalities. The outcome was favourable after treatment with spiramycin, levofloxacin and corticosteroids.<BR><B>CONCLUSIONS: </B>Few cases only (n=110) of Legionnaires' disease with cerebellar symptoms have been reported in the literature. The pathogenic mechanism behind neurological dysfunction in patients with Legionnaires' disease is unknown. Neurological symptoms improve with antibiotic therapy and corticosteroids. Extra-pulmonary forms of Legionnaires' disease are frequent, with neurological symptoms being the most common symptoms. Cerebellar dysfunction may be underestimated and requires appropriate management with antibiotic therapy and corticosteroid therapy. Recommendations for the management of Legionnaire's disease with severe extra-pulmonary symptoms are needed.