%0 Journal Article %T Microservices-Based Architecture to Support the Adaptive RECORDS-Trial. %A Nageba E %A Hilka M %A Gozlan R %A Dubiel J %A Baudoin C %A Daniel C %A Nageba E %A Hilka M %A Gozlan R %A Dubiel J %A Baudoin C %A Daniel C %J Stud Health Technol Inform %V 294 %N 0 %D May 2022 25 %M 35612077 暂无%R 10.3233/SHTI220458 %X Information systems used by platform trials should handle changes that are not predefined. Unfortunately, the technical architecture of most existing clinical data management systems (CDMS) do not support changes to be incorporated into an ongoing trial. Adaptive clinical trials need advanced architectural solutions setup to enable biomarker stratification and enrichment strategy necessary for the adaptive clinical trial operation. This short paper presents the microservices-based architecture solution that is used to run and support the adaptive RECORDS-Trial.