%0 Journal Article
%T Reliability of Drug-Drug Interaction Measurement on Real-Word Data: The ReMIAMes Project.
%A Duclos C
%A Griffon N
%A Daniel C
%A Bouzillé G
%A Delamarre D
%A Darmoni S
%A Toubiana L
%A Grosjean J
%A Duclos C
%A Griffon N
%A Daniel C
%A Bouzillé G
%A Delamarre D
%A Darmoni S
%A Toubiana L
%A Grosjean J
%J Stud Health Technol Inform
%V 294
%N 0
%D May 2022 25
%M 35612045
暂无%R 10.3233/SHTI220425
%X The ReMIAMes project proposes a methodological framework to provide a reliable and reproducible measurement of the frequency of drug-drug interactions (DDI) when performed on real-world data. This framework relies on (i) a fine-grained and contextualized definition of DDIs, (ii) a shared minimum information model to select the appropriate data for the correct interpretation of potential DDIs, (iii) an ontology-based inference module able to handle missing data to classify prescription lines with potential DDIs, (iv) a report generator giving the value of the measurement and explanations when potential false positive are detected due to a lack of available data. All the tools developed are intended to be publicly shared under open license.