%0 Case Reports %T Report of a Case of Creutzfeldt-Jakob Disease With an Unusual Quick Evolution. %A Fadili H %A Tazi R %A El Oury H %A El Aidaoui K %A Hazim A %A Fadili H %A Tazi R %A El Oury H %A El Aidaoui K %A Hazim A %J Cureus %V 14 %N 3 %D Mar 2022 %M 35415036 暂无%R 10.7759/cureus.22982 %X Creutzfeldt-Jakob disease is a rare, transmissible neurodegenerative disorder, most prevalent between the ages of 50 and 70 years old, that is incurable and fatal. It's caused by a slow, infectious protein agent-designated prion. The most common clinical presentations are sleep disturbances, personality changes, ataxia, aphasia, visual disturbances, weakness, and myoclonus combined with progressive dementia. Here we report the case of a patient with disturbance of consciousness, restlessness, and myoclonia who died two weeks after admission. The analysis of his cerebrospinal fluid reveals that the presence of 14-3-3 protein was positive, which supports the diagnosis of Creutzfeldt-Jakob disease. Our observation underscores the importance of the quick fatality of this case.