%0 Case Reports
%T Scleredema with biopsy-confirmed cardiomyopathy: A case report.
%A Nakatsuji M
%A Ishimaru N
%A Ohnishi J
%A Mizuki S
%A Kanzawa Y
%A Kawano K
%A Nakajima T
%A Kuroda M
%A Sano N
%A Kinami S
%J J Scleroderma Relat Disord
%V 6
%N 3
%D Oct 2021
%M 35387215
暂无%R 10.1177/23971983211013977
%X Scleredema is a rare cutaneous mucinosis characterized by diffuse swelling and non-pitting induration. A 63-year-old man reported a 5-year history of skin thickening of the trunk and a 3-week history of dyspnea. Echocardiography revealed diffuse hypokinesis. Skin biopsies obtained from the waist showed thickened dermis with mucin. Myocardial biopsies showed alcian blue-stained tissue between the muscle fibers. The patient was referred to a dermatologist for phototherapy. Cardiomyopathy should be considered in patients with scleredema. Scleredema usually has a good prognosis; however, the mortality risk could be high when accompanied by cardiomyopathy.