%0 English Abstract
%T [Descriptive cross-sectional study assessing the clinical and paraclinic profiles of monoclonal gammopathies in an agricultural region of Souss-Massa, Morocco].
%A Maataoui AE
%A Taoufiq A
%A Fares S
%A Sokori K
%A Maataoui AE
%A Taoufiq A
%A Fares S
%A Sokori K
%A Maataoui AE
%A Taoufiq A
%A Fares S
%A Sokori K
%J Pan Afr Med J
%V 41
%N 0
%D 2022
%M 35371382
暂无%R 10.11604/pamj.2022.41.69.32470
%X <B>UNASSIGNED: </B>given the lack of information about monoclonal gammopathies, our primary study outcome was to describe the epidemiological, clinical and biochemical profiles of monoclonal gammopathies in the Souss-Massa region, in southern Morocco.<BR><B>UNASSIGNED: </B>we conducted a retrospective study, by selecting only complete medical records. We used records of patients diagnosed with monoclonal gammopathy at the local oncology center during a period of over 10 years.<BR><B>UNASSIGNED: </B>one hundred and seventeen patients were included in the study, with a high male predominance (65%) and a male/female sex-ratio of 1.85. The average age of our study population was 61.44 (ET 14.54) years. Diagnoses (based on frequency) included: multiple myeloma 82.0% (n=96), solitary plasmacytoma 8.5% (n=10), monoclonal gammopathies of undetermined significance 2.6% (n=3), lymphoma 2.5% (n=3), secondary plasma cell leukaemia 1.7% (n=2), Waldenström´s disease 1.7%(n=2) and chronic lymphoid leukemia (n=1). The isotype distribution was as follows: IgG Kappa 33.7% (n=28), IgG lambda 21.7% (n=18), IgA Kappa 12.0% (n=10), IgA lambda 7.2% (n=6), IgM kappa 3.6% (n=3), and IgD lambda 2.4% (n=2). Biconal peak was reached in two cases, with a percentage of 2.4%.<BR><B>UNASSIGNED: </B>diagnostic delay was observed compared to international studies due to the unavailability of electrophoresis in the care structures.