%0 Case Reports
%T Missense Variant E1295K of Sodium Channel SCN5A Associated With Recurrent Ventricular Fibrillation and Myocardial Inflammation.
%A Poller W
%A Escher F
%A Haas J
%A Heidecker B
%A Schultheiss HP
%A Attanasio P
%A Skurk C
%A Haghikia A
%A Meder B
%A Klaassen S
%A Poller W
%A Escher F
%A Haas J
%A Heidecker B
%A Schultheiss HP
%A Attanasio P
%A Skurk C
%A Haghikia A
%A Meder B
%A Klaassen S
%J JACC Case Rep
%V 4
%N 5
%D Mar 2022 2
%M 35257103
暂无%R 10.1016/j.jaccas.2022.01.016
%X SCN5A was considered an exclusively cardiac expressed ion channel but discovered to also act as a novel innate immune sensor. We report on a young SCN5A variant carrier with recurrent ventricular fibrillation and massive myocardial inflammation whose peculiar clinical course is highly suggestive of such a dual role of SCN5A. (Level of Difficulty: Advanced.).