%0 Case Reports %T Avoidance of surgery for head and neck infantile myofibromatosis using imatinib monotherapy. %A Pattisapu P %A Wenger TL %A Dahl JP %A Bly RA %A Bonilla-Velez J %A Wu N %A Hall A %A Rudzinski ER %A Perkins JA %J Clin Case Rep %V 10 %N 2 %D Feb 2022 %M 35154723 暂无%R 10.1002/ccr3.5382 %X Describe a novel use for a kinase inhibitor, imatinib, in young children with a known activated somatic mutation in PDGFR-beta. Two patients with infantile myofibromatosis treated with imatinib. Case description of evaluation, diagnosis and treatment decisions for infantile myfibromatosis of the head and neck. Description of medical therapy for infantile myofibromatosis in these patients. For function threatening myofibromas of a known genotype, in infants, targeted medical therapy is a treatment option.