%0 Journal Article
%T Oocyte and embryo cryopreservation before gonadotoxic treatments: Principles of safe ovarian stimulation, a systematic review.
%A Ozcan MC
%A Snegovskikh V
%A Adamson GD
%J Womens Health (Lond)
%V 18
%N 0
%D Jan-Dec 2022
%M 35130799
暂无%R 10.1177/17455065221074886
%X Review the safety of fertility preservation through ovarian stimulation with oocyte or embryo cryopreservation, including cycle and medication options.<BR>A systematic review of peer-reviewed sources revealed 2 applicable randomized control trials and 60 cohort studies as well as 20 additional expert opinions or reviews.<BR>The capacity for future family building is important for the majority of reproductive age people, despite life-altering medical or oncologic diagnosis. Modern fertility preservation generates a high rate of oocyte yield while utilizing protocols that can be started at multiple points in the menstrual cycle and suppressing supra-physiologic levels of estrogen. Finally, more than one quarter of fertility preservation patients will return to later utilize fertility services.<BR>For most patients, fertility preservation can safely be pursued and completed within 2 weeks without affecting disease severity or long-term survival.