%0 Case Reports %T Huge mesenteric fibromatosis presenting with intestinal perforation and acute diffuse peritonitis: a case report. %A Xu Y %A Duan Z %A Hu W %A Zhu K %A You J %A Abe M %A Chen P %A Zhang Q %A Zong L %A Xu Y %A Duan Z %A Hu W %A Zhu K %A You J %A Abe M %A Chen P %A Zhang Q %A Zong L %J Transl Cancer Res %V 9 %N 9 %D Sep 2020 %M 35117931 %F 0.496 %R 10.21037/tcr-19-1151 %X Mesenteric fibromatosis is a locally invasive myofibroblastic proliferation and rarely metastasize to other organs. Hollow organ perforation and acute diffuse peritonitis caused by mesenteric fibromatosis rarely occurred. Here we report a case of huge mesenteric fibromatosis who complained a paroxysmal epigastric pain, and CT scan showed a huge mass, pneumoperitoneum and ascites. An urgent laparotomy showed an intro-abdominal mass and perforation locating at the jejunum. Postoperative histology confirmed it to be mesenteric fibromatosis. With one-year follow-up, the patient had no recurrence. We wish to share our treating experience of this interesting case because it did not belong to a typical type but presenting with acute diffuse peritonitis, and total resection and R0 margin is a key to treat acute case. This atypical one has not been reported in the literature till now.