%0 Journal Article
%T Chemoselective N-acylation of indoles using thioesters as acyl source.
%A Du T
%A Wei X
%A Xu H
%A Zhang X
%A Fang R
%A Yuan Z
%A Liang Z
%A Li Y
%A Du T
%A Wei X
%A Xu H
%A Zhang X
%A Fang R
%A Yuan Z
%A Liang Z
%A Li Y
%J Beilstein J Org Chem
%V 18
%N 0
%D 2022
%M 35096177
%F 2.544
%R 10.3762/bjoc.18.9
%X The selective acylation of indoles often requires sensitive and reactive acyl chloride derivatives. Here, we report a mild, efficient, functional group tolerant, and highly chemoselective N-acylation of indoles using thioesters as a stable acyl source. A series of indoleamides have been obtained with moderate to good yields. In addition, heterocycles, such as carbazole, can also be used as nucleophiles in this reaction.