%0 Journal Article %T Development of the gonadotropin-releasing hormone system. %A Duittoz AH %A Forni PE %A Giacobini P %A Golan M %A Mollard P %A Negrón AL %A Radovick S %A Wray S %J J Neuroendocrinol %V 34 %N 5 %D 05 2022 %M 35067985 %F 3.87 %R 10.1111/jne.13087 %X This review summarizes the current understanding of the development of the neuroendocrine gonadotropin-releasing hormone (GnRH) system, including discussion on open questions regarding (1) transcriptional regulation of the Gnrh1 gene; (2) prenatal development of the GnRH1 system in rodents and humans; and (3) paracrine and synaptic communication during migration of the GnRH cells.