%0 Journal Article %T Honeycomb Epithelial Edema Associated With Rho Kinase Inhibition: A Case Series and Review of the Literature. %A Lyons LJ %A Wu KY %A Baratz KH %A Sit AJ %J Cornea %V 41 %N 2 %D Feb 2022 1 %M 35037906 %F 3.152 %R 10.1097/ICO.0000000000002694 %X UNASSIGNED: The Rho kinase inhibitor netarsudil is a recently approved therapeutic option for the management of increased intraocular pressure in the United States. Although phase 3 clinical trials noted corneal changes related to the medication-namely, nonvisually-significant corneal verticillata-descriptions of a unique form of cystic epithelial edema began to surface as netarsudil (and its sister drug ripasudil, approved in Japan) gained widespread use. This series adds 3 new cases and reviews the current literature on this unique side effect.