%0 Journal Article
%T Local radiotherapy versus nonradiotherapy to distant lesions for metastatic nasopharyngeal carcinoma: Retrospective cohort study.
%A Yang L
%A Xue Y
%A Wei Z
%A Ren K
%A Liu Z
%A Chang T
%A Peng X
%A Su Y
%A Li Y
%J Head Neck
%V 44
%N 3
%D 03 2022
%M 34962007
%F 3.821
%R 10.1002/hed.26953
%X To evaluate the efficiency of local radiotherapy to metastatic lesions in patients with metastatic nasopharyngeal carcinoma (mNPC).<BR>The overall survival was observed and compared for mNPC patients who received local radiotherapy versus nonradiotherapy to metastatic lesions by using the Kaplan-Meier method and Cox analysis.<BR>One hundred and nine patients with NPC were involved in this study, with 61 (56.0%) received radiotherapy to metastatic sites and 48 (44.0%) did not receive radiotherapy to metastatic sites. The 2- and 5-year OS for patients who received local radiotherapy to metastatic lesions were 65.8% and 35.7%, and for patients who did not receive radiotherapy to metastatic lesions were 45.3% and 26.2%. The multivariable adjusted hazard radios for local radiotherapy versus nonradiotherapy to metastatic lesions were 0.482 (95% confidence interval is 0.278-0.834, p = 0.009).<BR>Local radiotherapy to metastatic lesions might be a protective factor for patients with mNPC.