%0 Journal Article
%T Application of Programmable Tetrahedral Framework Nucleic Acid-Based Nanomaterials in Neurological Disorders: Progress and Prospects.
%A Chen X
%A Xie Y
%A Liu Z
%A Lin Y
%A Chen X
%A Xie Y
%A Liu Z
%A Lin Y
%J Front Bioeng Biotechnol
%V 9
%N 0
%D 2021
%M 34900971
%F 6.064
%R 10.3389/fbioe.2021.782237
%X Tetrahedral framework nucleic acid (tFNA), a special DNA nanodevice, is widely applied in diverse biomedical fields. Due to its high programmability, biocompatibility, tissue permeability as well as its capacity for cell proliferation and differentiation, tFNA presents a powerful tool that could overcome potential barriers in the treatment of neurological disorders. This review evaluates recent studies on the use and progress of tFNA-based nanomaterials in neurological disorders.